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Chloroquine or hydroxychloroquine either stabilized symptoms or controlled neurological symptoms in 10 of 12 patients.Two patients failed to respond. Cerebrospinal fluid abnormalities,including lymphocytosis,were seen in 3 patients.Magnetic resonance imaging with gadolinium was most helpful in supporting the diagnosis of sarcoidosis and monitoring the course of the disease.Chloroquine and hydroxychloroquine are effective in controlling neurological sarcoidosis in those patients who fail to respond to corticosteroids or develop severe side effects.Ocular toxic effects from chloroquine or hydroxychloroquine were not observed. |
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